![]() ![]() This method exploits the analogy between treatment networks and electrical networks to construct the network meta-analysis model accounting for the correlated treatment effects in multi-arm trials. The netmeta package in R is based on a novel approach for network meta-analysis that follows the graph-theoretical methodology. Assessing evidence inconsistency in mixed treatment comparisons.J Amer Statist Assoc2006, 101: 447-459 Netmeta package – performing NMA in R Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies.Res Synth Meth2012, 3: 98-110 Higgins JPT, Jackson D, Barrett JK, Lu G, Ades AE, White IR. Consistency and inconsistency in network meta-analysis: model estimation using multivariate meta-regression.Res Synth Meth2012, 3: 111-125 White IR, Barrett JK, Jackson D, Higgins JPT. Multivariate random-effects meta-regression: Updates to mvmeta.The STATA Journal2011, 11: 255-270 The command contains also an option that enables the estimation of ranking probabilities. Both consistency and inconsistency models (the ‘design-by-treatment model’ or ‘Lu & Ades model’) have been implemented as well as network meta-regression models that can incorporate covariates. The command can perform fixed and random effects network meta-analysis assuming either a common or different between-study variances across comparisons. The mvmeta command in STATA employs a recent approach to network meta-analysis that handles the different treatment comparisons appeared in studies as different outcomes. Available Online Material & Software for Network Meta-Analysis mvmeta command – performing NMA in STATA ![]()
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